• Can bone mineral density loss in the non-weight bearing distal forearm predict mortality? 

      Hauger, Annette Vogt; Bergland, Astrid; Holvik, Kristin; Emaus, Nina; Strand, Bjørn Heine (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-30)
      <i>Purpose</i> - Low bone mineral density (BMD) is associated with increased risk of fractures and mortality. We investigated if rate of BMD loss in the distal forearm over seven years predicted mortality.<br><br> <i>Methods</i> - 1725 postmenopausal women and 1879 men aged 50–74 who participated in the longitudinal Tromsø Study waves 4 (1994–95) and 5 (2001−2002) were included. Cox regression ...
    • Cause-specific excess mortality after hip fracture: the Norwegian Epidemiologic Osteoporosis Studies (NOREPOS) 

      Holvik, Kristin; Ellingsen, Christian Lycke; Solbakken, Siri Marie; Finnes, Trine Elisabeth; Talsnes, Ove; Grimnes, Guri; Tell, Grethe Seppola; Søgaard, Anne-Johanne; Meyer, Haakon Eduard (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-31)
      Background Information on cause of death may help appraise the degree to which the high excess mortality after hip fracture refects pre-existing comorbidities or the injury itself. We aimed to describe causes of death and causespecifc excess mortality through the frst year after hip fracture.<p> <p>Methods For studying the distribution of causes of death by time after hip fracture, we calculated ...
    • Forearm fractures–are we counting them all? An attempt to identify and include the missing fractures treated in primary care 

      Dahl, Cecilie; Ohm, Eyvind; Solbakken, Siri Marie; Anwar, Nudrat; Holvik, Kristin; Madsen, Christian; Frihagen, Frede; Bjørnerem, Åshild Marit; Nissen, Frida Igland; Solberg, Lene Bergendal; Omsland, Tone Kristin (Journal article; Tidsskriftartikkel, 2023-07-07)
      Objective: Norway has a high incidence of forearm fractures, however, the incidence rates based on secondary care registers can be underestimated, as some fractures are treated exclusively in primary care. We estimated the proportion of forearm fracture diagnoses registered exclusively in primary care and assessed the agreement between diagnosis for forearm fractures in primary and secondary care. ...
    • Grip strength in men and women aged 50–79 years is associated with non-vertebral osteoporotic fracture during 15 years follow-up: The Tromsø Study 1994–1995 

      Søgaard, Anne-Johanne; Magnus, Jeanette H.; Bjørnerem, Åshild; Holvik, Kristin; Ranhoff, Anette Hylen; Emaus, Nina; Meyer, Haakon E; Strand, Bjørn Heine (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-25)
      <p><i>Summary - </i>In 50–79-year-olds who participated in the Tromsø Study (1994–1995), the risk of non-vertebral osteoporotic fractures during 15 years follow-up increased by 22% in men and 9% in women per 1 SD lower grip strength. The strongest association was observed in men aged 50–64 years. <p><i>Introduction - </i>We aimed to explore whether low grip strength was associated with increased ...
    • Impact of total hip replacements on the incidence of hip fractures in Norway during 1999-2019. A NOREPOS study 

      Kjeldgaard, Helena Kames; Meyer, Haakon E.; O’Flaherty, Martin; Apalset, Ellen Margrete; Dahl, Cecilie; Emaus, Nina; Fenstad, Anne Marie; Furnes, Ove; Gjertsen, Jan-Erik; Hoff, Mari; Schei, Berit; Søgaard, Anne-Johanne; Tell, Grethe S.; Holvik, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-25)
      The knowledge about why hip fracture rates in Norway have declined is sparse. Concurrent with decreasing hip fracture rates, the rates of total hip replacements (THRs) have increased. We wanted to investigate if hip fracture rates continued to decline, and whether the increase in THRs had any influence on this decline, assuming that living with a hip prosthesis precludes fracture of the operated ...
    • Individual Variation in Adaptive Immune Responses and Risk of Hip Fracture-A NOREPOS Population-Based Cohort Study 

      Dahl, Jesper; Holvik, Kristin; Heldal, Einar; Grimnes, Guri; Hoff, Mari; Finnes, Trine; Apalset, Ellen Margrete; Meyer, Haakon E (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-22)
      Immune‐mediated bone loss significantly impacts fracture risk in patients with autoimmune disease, but to what extent individual variations in immune responses affect fracture risk on a population level is unknown. To examine how immune responses relate to risk of hip fracture, we looked at the individual variation in a post‐vaccination skin test response that involves some of the immune pathways ...
    • Low Serum Levels of 25-Hydroxyvitamin D Predict Hip Fracture in the Elderly: A NOREPOS Study 

      Holvik, Kristin; Ahmed, Luai Awad; Forsmo, Siri; Gjesdal, Clara Gram; Grimnes, Guri; Samuelsen, Sven Ove; Schei, Berit; Blomhoff, Rune; Tell, Grethe S; Meyer, Haakon E (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-08-01)
      <p><i>Background</i>: Despite considerable interest, the relationship between circulating 25-hydroxyvitamin D and the risk of hip fracture is not fully established.</p> <p><i>Objective</i>: The objective of the study was to study the association between serum 25-hydroxyvitamin D concentrations [s-25(OH)D] and the risk of hip fracture in Norway, a high-latitude country that has some of the highest ...
    • National health registries – a ‘goldmine’ for studying non-communicable disease occurrence in Norway – the NCDNOR project 

      Nystad, Wenche; Hjellvik, Vidar; Larsen, Inger Kristin; Robsahm, Trude Eid; Sund, Erik Reidar; Krokstad, Steinar; Hopstock, Laila Arnesdatter; Grimsgaard, Anne Sameline; Langhammer, Arnulf; Bramness, Jørgen Gustav; Wisløff, Torbjørn; Lergenmuller, Simon; Dalene, Knut Eirik; Meyer, Haakon Eduard; Holvik, Kristin; Helgeland, Jon; Karlstad, Øystein; Ariansen, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-10)
      To estimate occurrence of non-communicable diseases (NCDs) over the life-course in the Norwegian population, national health registries are a vital source of information since they fully represent the entire non-institutionalised population. However, as they are mainly established for administrative purposes, more knowledge about how NCDs are recorded in the registries is needed. To establish this, ...
    • Osteoporosis and osteopenia in the distal forearm predicts all-cause mortality independent of grip strength: 22-year follow-up in the population-based Tromsø Study 

      Hauger, Annette Vogt; Bergland, Astrid; Holvik, Kristin; Ståhle, Agneta; Emaus, Nina; Strand, Bjørn Heine (Journal article; Tidsskriftartikkel, 2018-08-09)
      <p><i>Introduction:</i> To investigate if bone mineral density (BMD) levels of the distal forearm, consistent with osteopenia and osteoporosis, can predict mortality and if grip strength is an effect modifier.<p> <p><i> Methods:</i> The study population constituted 6565 participants aged 50–79 years at baseline in the Tromsø Study wave 4 conducted in 1994–1995. Forearm BMD measured by SXA was ...
    • Physical capability, physical activity, and their association with femoral bone mineral density in adults aged 40 years and older: The Tromsø study 2015–2016 

      Hauger, Annette Vogt; Holvik, Kristin; Bergland, Astrid; Ståhle, Agneta; Emaus, Nina; Morseth, Bente; Strand, Bjørn Heine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-16)
      Summary: Since muscles can influence bone growth and vice versa, we examined if level of physical activity and physical capability tests can predict areal bone mineral density (aBMD). Both high activity level and good test performance were associated with higher aBMD, especially in women. <p> <p>Introduction: Muscle influences bone formation and vice versa. Tests of physical capability and level ...
    • Sodium and Potassium Intake Assessed by Spot and 24-h Urine in the Population-Based Tromsø Study 2015–2016 

      Meyer, Haakon E; Johansson, Lars; Eggen, Anne Elise; Johansen, Heidi; Holvik, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-16)
      Reduction of salt intake is a public health priority and necessitates the surveillance of salt intake in the population. The validity of salt intake assessed by dietary surveys is generally low. We, therefore, aimed to estimate salt intake by 24-h urine collection and to assess the usefulness of spot urine collection for surveillance purposes. In the population-based Tromsø Study 2015–2016, 493 men ...
    • Urban–Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study 

      Solbakken, Siri Marie; Magnus, Jeanette H.; Meyer, Haakon E; Dahl, Cecilie; Stigum, Hein; Søgaard, Anne-Johanne; Holvik, Kristin; Tell, Grethe S.; Emaus, Nina; Forsmo, Siri; Gjesdal, Clara Gram; Schei, Berit; Vestergaard, Peter; Omsland, Tone Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-09)
      Higher hip fracture incidence in urban than in rural areas has been demonstrated, but urban–rural differences in posthip fracture mortality have been less investigated, and the results are disparate. Hence, the aims of the present register‐based cohort study were to examine possible urban–rural differences in short‐ and long‐term mortality in Norwegian hip fracture patients and their potential ...